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Toxicity and Safety Pharmacology
Toxicity and Safety Pharmacology in rodents and zebra fish
The in vivo preclinical animal facility at Aaranya Biosciences offers a full range of non-GLP safety pharmacology and toxicology evaluations in rats, mice, rabbits and zebra fish. Toxicity study based on acute, subacute and chronic are conducted and route of administration of drugs like oral, nasal, intravenous, intramuscular, ocular, subcutaneous are done based customer needs. Pharmacokinetic and toxicokinetic studies are done in biological samples includes plasma, blood, serum, organs. Also carry out protein based expression profile and gene regulation studies in specific tissues. Measure biomarkers using ELISA, spectrophotometer, chromatographic methods. We also deal in diseases relating to cardiovascular, CNS, pulmonary, renal, gastrointestinal, and autonomic nervous system safety pharmacology assessments and measure organ specific toxicity using cell lines or ex-vivo studies. Panel of biomarkers as specified by clients are carried

The toxicologists and study monitors at Aaranya Biosciences have experience in a variety of compounds and therapeutic areas to monitor from study initiation and project comppletion.

We monitor studies; obtain competitive bids with comparisons based on critical milestones to design and review study protocols, considering dose selection, animal models, regimen, overall design and regulatory compliance.

Aaranya Biosciences has experience with acute, sub-chronic, and chronic toxicology, all classes of compounds, including pharmaceuticals, recombinant proteins and other biotech products.

General Toxicology
General Toxicology

Many of the toxicities are functional in nature and/or in origin. Whereas pharmacological responses tend to be fairly rapid in onset, and are therefore detectable after a single

MTD /DRF/TK
MTD /DRF/TK

Toxico-kinetics (TK): In brief, TK provides an estimate assessment of the rate with which a drug which enters along with the relative effect on the body. This niche

Target Organ toxicity / Immunotoxicity
Target Organ toxicity / Immunotoxicity

Immunotoxicity- The primary gray area of immunotoxicity testing strategies is in deciding if additional immunotoxicity testing is needed (assays beyond that normally done for standard toxicity studies [STS]).

Ocular Toxicity / Dermal Toxicity
Ocular Toxicity / Dermal Toxicity

Ocular Toxicity- "Draize Test" to test the irritation and pain in the eyes and is a reliable predictor of human response.

Dermal Toxicity- Dermal sensitization for immune

Genetic Toxicity
Genetic Toxicity

DNA can be damaged through normal biologic process or due the result of interaction of DNA directly /indirectly with chemical, physical or biological agents.

The aim of Aaranya Biosciences

Inhalation toxicity / Eco-toxicology
Inhalation toxicity / Eco-toxicology

The mode of transmission might be due to contact (physical contact, airborne inhalation) with an infected individual or secretion (sputum or other bodily fluids). Transmission can also occur

Biocompatability Studies
Biocompatability Studies

The biocompatibility testing procedures in Aaranya Biosciences are designed to detect the nonspecific, biologically reactive, physical or chemical characteristics of medical products or the materials used in their

Safety battery Tests
Safety battery Tests

Experts at Aaranya Biosciences use a comprehensive safety pharmacology testing services.

We’re ready to listen to you and then design just the right studies to help with the registration

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